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Anesthetic experience: congenital methemoglobinemia due to hemoglobin M

Journal of Dental Anesthesia and Pain Medicine 2021³â 21±Ç 5È£ p.471 ~ 474
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¸®Çö¼ö ( Ri Hyun-Su ) - Kyungpook National University Hospital Department of Anesthesiology and Pain Medicine
¹Ú¿µÁ¦ ( Park Young-Je ) - Kyungpook National University Hospital Department of Anesthesiology and Pain Medicine
Àü¿µÈÆ ( Jeon Young-Hoon ) - Kyungpook National University Hospital Department of Anesthesiology and Pain Medicine

Abstract


Methemoglobinemia is rare. It is classified into two types: congenital methemoglobinemia and acquired methemoglobinemia. Methemoglobin is incapable of binding oxygen, leading to complications such as cyanosis, dyspnea, headache, and heart failure. In the present case, a 35-year-old man with congenital methemoglobinemia underwent general anesthesia for thyroidectomy. The patient was diagnosed with hemoglobin M at 7 years of age. Ventilation was performed with FiO2 1.0. Arterial blood gas analysis showed that the pH was 7.4, PaO2 439 mmHg, PaCO2 40.5 mmHg, oxyhemoglobin level of 83.2%, and methemoglobin level of 15.5%. The patient had a stable course, although cyanosis was observed during surgery.

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General Anesthesia; Hemoglobin M; Methemoglobin; Methemoglobinemia

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